2nd Edition of Public Health World Conference (PHWC) 2026

Abstract

Stroke is a global leading cause of death. Carotid artery stenosis (CAS) is an early indicator of stroke. Currently, carotid Doppler ultrasound is the preferred option for assessing CAS risk, but it is impractical to do so for the screening purpose. In this paper, the PulStroke program was initiated to transform the video motion analysis (VMA) developed by the authors into a potential commercial product, with the goal of completing the entire CAS screening process quickly. PulStroke is the world’s first fully-automated screening device for carotid artery stenosis. A user records a 20-second video clip using the device and, with just one simple screen touch, the video clip is automatically uploaded to the cloud for the CAS risk assessment. VMA analyzes the video clip and sends a risk report back to the user’s account in just 5 minutes. VMA technology is able to extract useful features from subtle pulsation on the neck and classify CAS and non-CAS subjects with acceptable sensitivity and specificity. This paper presents the methodology used to advance the technology readiness level from TRL 1 to TRL 6, highlighting the evolution of the PulStroke device from concept to product. As part of the technology maturity process, the PulStroke device was evaluated with target users invited to participate in the usability testing. This was crucial in assessing the PulStroke device's safety, effectiveness, and practicality in real-world settings. Most users found the PulStroke to be fully functional and easy to use, with a satisfaction rate of more than 88%. This strong approval indicates its user-friendly design and full potential to make an impact in the medical society. The PulStroke device could be incorporated into future clinical practice to provide the general public with quick and cost-effective CAS screening for the first time. PulStroke screening outcomes will allow early interventions (life style changes, medicine, or surgery) for millions of people, reducing healthcare costs and improving survival rates around the globe.