Drug Development or exploration of new lead compounds is always remain a fundamental field in health sciences. Other than engineering side which is generally for human comfort and convenience, the biological sciences is very crucial due to its direct involvement in human health. Drug resistance, environmental changes, emerging diseases and previously untreatable diseases with lesser side effects and better efficacy are main causes for the researchers/pharmacists to discover new bioactive compounds for drug development.
Electrified and thrilled by the above mentioned facts, we were interested to develop some novel bioactive heterocycles for drug development. In literature, Thiadiazines heterocycles have good biological insights but with lesser derivatives development due to its tricky nature. Therefore, we successfully synthesized and reported several potent activities on Thiadiazines recently (see references 1-6). Our newly developed Thiadiazines showed several biological activities including potent anti-leishmanial, anti-inflammatory, anti-cancer, urease inhibition, analgesic, antimicrobial etc and their primarily model testing as prodrug candidate has been also positively explored.