2nd Edition of Public Health World Conference (PHWC) 2026

Abstract

Objective: To investigate quality of life in children with autism spectrum disorder.This study aimed to evaluate the validity of existing QoL questionnaires for use with children with ASD aged 8–12 years.

Method: 200 children with autism spectrum disorder (male: 118, female: 82; 2~4 years old: 80, 5~7 years old: 87, 8~12 years old: 33) and 120 normal children (control group) are brought into this study. Separate path analyses were performed to evaluate models of QOL and Intelligent evaluation. The PedsQL (Pediatric Quality of Life Inventory) is a robust measure used with children with neurodevelopmental disorders.

Results in the study, the test group had lower scores on the PedsQL4.0 universality Core scale, in comparison with the control group. Behavior problems had a negative indirect effect on Community adaptation, mental health and school performance. And a lower intelligence-related quality of life for children with autism spectrum disorder and clinically significant autistic symptoms in comparison with children and fewer symptoms.The quality of life of children with autism spectrum disorder was lower than that of the normal group in the scores of physical functioning (62.30 ± 25.05),emotional functioning (53.57 ± 26.69),social functioning (44.63 ± 27.91)， and school functioning(38.69 ± 30.60).The totals cores of PedsQL were(49.86 ± 23.32),with the difference being significant(90.16±13.32、79.09±19.56、86.39±15.45、82.75±16.03、85.23 ±14.2，P<0.01).

Conclusions Results suggest greater impairment in adaptive functioning and emotional disorders. For high-functioning children with autism spectrum disorder, potential positive development played a significant role in rehabilitation, to achieve and maintain the best level of intervention.The severity of the disorder and social support coping strategies were related to Life self-care ability and adaptation, coping with intellectual obstacles seriously .Physicians are encouraged to evaluate for early treatment in the overall care plan.