Urbanization has accelerated at an unprecedented rate over the past century, leading to increased climate vulnerabilities, degraded ecosystems, and reduced quality of life for urban dwellers. This presentation focuses on urban green infrastructure (UGI) as a multifaceted, nature-based solution to address these interconnected challenges. UGI—encompassing urban forests, green roofs, rain gardens, permeable pavements, and connected green corridors—offers a range of co-benefits that extend beyond traditional gray infrastructure. The talk will first outline the current state of urban environmental degradation, highlighting data on heat island effects, stormwater runoff, and biodiversity loss in mid-sized to large cities globally. It will then delve into the scientific evidence supporting UGI’s role in mitigating climate risks: reducing urban temperatures by 2–5°C through evapotranspiration, capturing up to 80% of stormwater to prevent flooding, and sequestering carbon at rates comparable to rural forests. Additionally, the presentation will explore UGI’s contributions to enhancing ecosystem services, such as improving air quality by filtering particulate matter and pollutants, supporting pollinators and urban wildlife, and promoting mental and physical health through increased access to green spaces. Case studies from Portland (USA), Barcelona (Spain), and New Delhi (India) will be shared to illustrate successful UGI implementation, including policy frameworks, community engagement strategies, and cost-benefit analyses. The talk will conclude with actionable recommendations for urban planners, policymakers, and stakeholders to integrate UGI into city master plans, emphasizing the need for cross-sectoral collaboration, long-term monitoring, and equitable access to green spaces to ensure that the benefits of UGI reach all urban residents. By prioritizing UGI, cities can transition toward resilience, sustainability, and livability in the face of climate change.